Dorzolamide-d5


Catalog No. Size PriceQuantity
M24815-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Dorzolamide-d5 (L671152-d5) is the deuterium labeled Dorzolamide. Dorzolamide (L671152) is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity.

Product information

CAS Number: 1227097-70-2

Molecular Weight: 326.46

Formula: C10H18N2O4S3

Chemical Name: (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H,6H,7aH-1λ⁶-thieno[2,3-b]thiopyran-6-sulfonamide

Smiles: C[C@H]1C[C@H](NCC)C2=CC(SC2S1(=O)=O)S(N)(=O)=O

InChiKey: SGTTVZPWMKGBNU-FXQVNJNESA-N

InChi: InChI=1S/C10H18N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8-10,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-,9?,10?/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

Products are for research use only. Not for human use.

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