BCN-PEG3-VC-PFP ester


Catalog No. Size PriceQuantity
M24822-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 2353409-45-5

Molecular Weight: 819.81

Formula: C37H50F5N5O10

Chemical Name: 2,3,4,5,6-pentafluorophenyl (2S)-2-[(2S)-2-{3-[2-(2-{2-[({[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)amino]ethoxy}ethoxy)ethoxy]propanamido}-3-methylbutanamido]-5-(carbamoylamino)pentanoate

Smiles: CC(C)[C@H](NC(=O)CCOCCOCCOCCNC(=O)OCC1[C@@H]2CCC#CCC[C@H]12)C(=O)N[C@@H](CCCNC(N)=O)C(=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: ODFSIYMVJDIAIS-COWKONOXSA-N

InChi: InChI=1S/C37H50F5N5O10/c1-21(2)32(34(49)46-25(10-7-12-44-36(43)51)35(50)57-33-30(41)28(39)27(38)29(40)31(33)42)47-26(48)11-14-53-16-18-55-19-17-54-15-13-45-37(52)56-20-24-22-8-5-3-4-6-9-23(22)24/h21-25,32H,5-20H2,1-2H3,(H,45,52)(H,46,49)(H,47,48)(H3,43,44,51)/t22-,23+,24?,25-,32-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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