Description
BCN-PEG3-VC-PFP ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 2353409-45-5
Molecular Weight: 819.81
Formula: C37H50F5N5O10
Chemical Name: 2,3,4,5,6-pentafluorophenyl (2S)-2-[(2S)-2-{3-[2-(2-{2-[({[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)amino]ethoxy}ethoxy)ethoxy]propanamido}-3-methylbutanamido]-5-(carbamoylamino)pentanoate
Smiles: CC(C)[C@H](NC(=O)CCOCCOCCOCCNC(=O)OCC1[C@@H]2CCC#CCC[C@H]12)C(=O)N[C@@H](CCCNC(N)=O)C(=O)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey: ODFSIYMVJDIAIS-COWKONOXSA-N
InChi: InChI=1S/C37H50F5N5O10/c1-21(2)32(34(49)46-25(10-7-12-44-36(43)51)35(50)57-33-30(41)28(39)27(38)29(40)31(33)42)47-26(48)11-14-53-16-18-55-19-17-54-15-13-45-37(52)56-20-24-22-8-5-3-4-6-9-23(22)24/h21-25,32H,5-20H2,1-2H3,(H,45,52)(H,46,49)(H,47,48)(H3,43,44,51)/t22-,23+,24?,25-,32-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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