Eleutheroside B1


Catalog No. Size PriceQuantity
M24850-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.

Product information

CAS Number: 16845-16-2

Molecular Weight: 384.33

Formula: C17H20O10

Chemical Name: 6,8-dimethoxy-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one

Smiles: COC1=C2OC(=O)C=CC2=CC(OC)=C1OC1OC(CO)C(O)C(O)C1O

InChiKey: IKUQEFGEUOOPGY-UHFFFAOYSA-N

InChi: InChI=1S/C17H20O10/c1-23-8-5-7-3-4-10(19)26-14(7)16(24-2)15(8)27-17-13(22)12(21)11(20)9(6-18)25-17/h3-5,9,11-13,17-18,20-22H,6H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.

Products are for research use only. Not for human use.

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