Description
BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent.
Product information
CAS Number: 2290660-61-4
Molecular Weight: 497.38
Formula: C24H22Cl2N6O2
Chemical Name: 5-[(3,4-dichlorophenyl)methyl]-4-oxo-1-(piperidin-4-yl)-N-(pyridin-4-yl)-1H,4H,5H-pyrazolo[4,3-c]pyridine-7-carboxamide
Smiles: O=C(NC1C=CN=CC=1)C1=CN(CC2=CC(Cl)=C(Cl)C=C2)C(=O)C2C=NN(C3CCNCC3)C=21
InChiKey: BMOUOZDRMBLNSI-UHFFFAOYSA-N
InChi: InChI=1S/C24H22Cl2N6O2/c25-20-2-1-15(11-21(20)26)13-31-14-19(23(33)30-16-3-7-27-8-4-16)22-18(24(31)34)12-29-32(22)17-5-9-28-10-6-17/h1-4,7-8,11-12,14,17,28H,5-6,9-10,13H2,(H,27,30,33)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 125 mg/mL (251.32 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity.
Products are for research use only. Not for human use.
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