Description
Imiclopazine is a phenothiazine derivative with good sedative, analgesic, antiaggressive and antiemetic effects.
Product information
CAS Number: 7414-95-1
Molecular Weight: 558.99
Formula: C25H34Cl3N5OS
Chemical Name: 1-(2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethyl)-3-methylimidazolidin-2-one dihydrochloride
Smiles: Cl.Cl.CN1CCN(CCN2CCN(CCCN3C4=CC=CC=C4SC4=CC=C(Cl)C=C34)CC2)C1=O
InChiKey: PPSBKOXETNYGJD-UHFFFAOYSA-N
InChi: InChI=1S/C25H32ClN5OS.2ClH/c1-27-11-17-30(25(27)32)18-16-29-14-12-28(13-15-29)9-4-10-31-21-5-2-3-6-23(21)33-24-8-7-20(26)19-22(24)31;;/h2-3,5-8,19H,4,9-18H2,1H3;2*1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Imiclopazine shows multidrug-resistance (MDR)-reversal activity in P388 and P388/ADR cells, with EC50 values of both 200 μM.
Products are for research use only. Not for human use.
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