Description
Boc-Aminooxy-PEG4-CH2CO2H is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2028281-90-3
Molecular Weight: 367.39
Formula: C15H29NO9
Chemical Name: 1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10,13-pentaoxapentadecan-15-oic acid
Smiles: CC(C)(C)OC(=O)NOCCOCCOCCOCCOCC(O)=O
InChiKey: JVRAJIPQLHJVKM-UHFFFAOYSA-N
InChi: InChI=1S/C15H29NO9/c1-15(2,3)25-14(19)16-24-11-10-22-7-6-20-4-5-21-8-9-23-12-13(17)18/h4-12H2,1-3H3,(H,16,19)(H,17,18)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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