Hydroxy-PEG2-C2-PFP ester


Catalog No. Size PriceQuantity
M25106-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Hydroxy-PEG2-C2-PFP ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1820673-42-4

Molecular Weight: 344.23

Formula: C13H13F5O5

Chemical Name: 2,3,4,5,6-pentafluorophenyl 3-[2-(2-hydroxyethoxy)ethoxy]propanoate

Smiles: OCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F

InChiKey: FTFZBMSTIHCECX-UHFFFAOYSA-N

InChi: InChI=1S/C13H13F5O5/c14-8-9(15)11(17)13(12(18)10(8)16)23-7(20)1-3-21-5-6-22-4-2-19/h19H,1-6H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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