Dde Biotin-PEG4-azide


Catalog No. Size PriceQuantity
M25147-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1802907-93-2

Molecular Weight: 695.87

Formula: C32H53N7O8S

Chemical Name: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[19-azido-15-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,6,9,12-tetraoxa-16-azanonadec-15-en-1-yl]pentanamide

Smiles: CC1(C)CC(=O)C(=C(O)C1)C(CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)=NCCCN=[N+]=[N-]

InChiKey: WAGQAVIHHLSDJC-NTEGBPAGSA-N

InChi: InChI=1S/C32H53N7O8S/c1-32(2)20-25(40)29(26(41)21-32)23(34-9-5-10-36-39-33)8-12-44-14-16-46-18-19-47-17-15-45-13-11-35-28(42)7-4-3-6-27-30-24(22-48-27)37-31(43)38-30/h24,27,30,40H,3-22H2,1-2H3,(H,35,42)(H2,37,38,43)/b34-23+/t24-,27-,30-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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