Propargyl-PEG11-methane


Catalog No. Size PriceQuantity
M25161-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2250411-18-6

Molecular Weight: 554.67

Formula: C26H50O12

Chemical Name: 2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaoctatriacont-37-yne

Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

InChiKey: XEWWWOYVKPSCKC-UHFFFAOYSA-N

InChi: InChI=1S/C26H50O12/c1-3-4-28-7-8-30-11-12-32-15-16-34-19-20-36-23-24-38-26-25-37-22-21-35-18-17-33-14-13-31-10-9-29-6-5-27-2/h1H,4-26H2,2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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