Carboxy-PEG4-sulfonic acid


Catalog No. Size PriceQuantity
M25169-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Carboxy-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1817735-25-3

Molecular Weight: 330.35

Formula: C11H22O9S

Chemical Name: 1-sulfo-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCS(O)(=O)=O

InChiKey: AIQWRGDWHOOSMN-UHFFFAOYSA-N

InChi: InChI=1S/C11H22O9S/c12-11(13)1-2-17-3-4-18-5-6-19-7-8-20-9-10-21(14,15)16/h1-10H2,(H,12,13)(H,14,15,16)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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