Azido-PEG2-hydrazide-Boc


Catalog No. Size PriceQuantity
M25181-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2100306-56-5

Molecular Weight: 317.34

Formula: C12H23N5O5

Chemical Name: N'-{3-[2-(2-azidoethoxy)ethoxy]propanoyl}(tert-butoxy)carbohydrazide

Smiles: CC(C)(C)OC(=O)NNC(=O)CCOCCOCCN=[N+]=[N-]

InChiKey: JYNHRXFEKXQQDG-UHFFFAOYSA-N

InChi: InChI=1S/C12H23N5O5/c1-12(2,3)22-11(19)16-15-10(18)4-6-20-8-9-21-7-5-14-17-13/h4-9H2,1-3H3,(H,15,18)(H,16,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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