Amino-PEG2-C2-hydrazide-Boc


Catalog No. Size PriceQuantity
M25188-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2100306-60-1

Molecular Weight: 291.34

Formula: C12H25N3O5

Chemical Name: N'-{3-[2-(2-aminoethoxy)ethoxy]propanoyl}(tert-butoxy)carbohydrazide

Smiles: CC(C)(C)OC(=O)NNC(=O)CCOCCOCCN

InChiKey: UDVYFYDWDLXHPA-UHFFFAOYSA-N

InChi: InChI=1S/C12H25N3O5/c1-12(2,3)20-11(17)15-14-10(16)4-6-18-8-9-19-7-5-13/h4-9,13H2,1-3H3,(H,14,16)(H,15,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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