Description
Benzyl-PEG6-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2148295-93-4
Molecular Weight: 471.58
Formula: C24H41NO8
Chemical Name: tert-butyl N-(1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl)carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCC1C=CC=CC=1
InChiKey: UCUVQZHCUVOJHX-UHFFFAOYSA-N
InChi: InChI=1S/C24H41NO8/c1-24(2,3)33-23(26)25-9-10-27-11-12-28-13-14-29-15-16-30-17-18-31-19-20-32-21-22-7-5-4-6-8-22/h4-8H,9-21H2,1-3H3,(H,25,26)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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