BDP FL-PEG5-propargyl


Catalog No. Size PriceQuantity
M25215-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BDP FL-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2093197-93-2

Molecular Weight: 549.41

Formula: C27H38BF2N3O6

Chemical Name: 2,2-difluoro-10,12-dimethyl-4-{2-[(3,6,9,12,15-pentaoxaoctadec-17-yn-1-yl)carbamoyl]ethyl}-1λ⁵,3-diaza-2-boratricyclo[7.3.0.0³,⁷]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide

Smiles: CC1C=C(C)C2=CC3=CC=C(CCC(=O)NCCOCCOCCOCCOCCOCC#C)N3[B-](F)(F)[N+]=12

InChiKey: GPYLESDPNBDJRD-UHFFFAOYSA-N

InChi: InChI=1S/C27H38BF2N3O6/c1-4-10-35-12-14-37-16-18-39-19-17-38-15-13-36-11-9-31-27(34)8-7-24-5-6-25-21-26-22(2)20-23(3)32(26)28(29,30)33(24)25/h1,5-6,20-21H,7-19H2,2-3H3,(H,31,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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