Azido-PEG3-phosphonic acid ethyl ester


Catalog No. Size PriceQuantity
M25239-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1337527-24-8

Molecular Weight: 339.33

Formula: C12H26N3O6P

Chemical Name: diethyl (2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)phosphonate

Smiles: CCOP(=O)(CCOCCOCCOCCN=[N+]=[N-])OCC

InChiKey: FPXYMBISZVJSOJ-UHFFFAOYSA-N

InChi: InChI=1S/C12H26N3O6P/c1-3-20-22(16,21-4-2)12-11-19-10-9-18-8-7-17-6-5-14-15-13/h3-12H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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