Description
Bis-Tos-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 42749-27-9
Molecular Weight: 590.70
Formula: C26H38O11S2
Chemical Name: 17-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl 4-methylbenzene-1-sulfonate
Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOS(=O)(=O)C1C=CC(C)=CC=1
InChiKey: ZIZXHPCBPDNLDD-UHFFFAOYSA-N
InChi: InChI=1S/C26H38O11S2/c1-23-3-7-25(8-4-23)38(27,28)36-21-19-34-17-15-32-13-11-31-12-14-33-16-18-35-20-22-37-39(29,30)26-9-5-24(2)6-10-26/h3-10H,11-22H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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