Bromoacetamido-C2-PEG2-NH-Boc


Catalog No. Size PriceQuantity
M25271-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bromoacetamido-C2-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 182244-33-3

Molecular Weight: 369.25

Formula: C13H25BrN2O5

Chemical Name: tert-butyl N-(2-{2-[2-(2-bromoacetamido)ethoxy]ethoxy}ethyl)carbamate

Smiles: CC(C)(C)OC(=O)NCCOCCOCCNC(=O)CBr

InChiKey: BLSNVTJXXUWHQT-UHFFFAOYSA-N

InChi: InChI=1S/C13H25BrN2O5/c1-13(2,3)21-12(18)16-5-7-20-9-8-19-6-4-15-11(17)10-14/h4-10H2,1-3H3,(H,15,17)(H,16,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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