endo-BCN-PEG3-NH-Boc


Catalog No. Size PriceQuantity
M25272-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

endo-BCN-PEG3-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1807501-84-3

Molecular Weight: 468.58

Formula: C24H40N2O7

Chemical Name: {bicyclo[6.1.0]non-4-yn-9-yl}methyl N-(2-{2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}ethyl)carbamate

Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCNC(=O)OCC1C2CCC#CCCC21

InChiKey: TUOLXDJYWZRBJY-UHFFFAOYSA-N

InChi: InChI=1S/C24H40N2O7/c1-24(2,3)33-23(28)26-11-13-30-15-17-31-16-14-29-12-10-25-22(27)32-18-21-19-8-6-4-5-7-9-20(19)21/h19-21H,6-18H2,1-3H3,(H,25,27)(H,26,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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