Description
Amine-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2306109-91-9
Molecular Weight: 432.55
Formula: C20H40N4O6
Chemical Name: N-(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide
Smiles: C[C@@H]1NC(=O)N[C@@H]1CCCCCC(=O)NCCOCCOCCOCCOCCN
InChiKey: DQZZCBCJTNOZDL-ZWKOTPCHSA-N
InChi: InChI=1S/C20H40N4O6/c1-17-18(24-20(26)23-17)5-3-2-4-6-19(25)22-8-10-28-12-14-30-16-15-29-13-11-27-9-7-21/h17-18H,2-16,21H2,1H3,(H,22,25)(H2,23,24,26)/t17-,18+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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