Bromoacetamido-PEG3-C2-acid


Catalog No. Size PriceQuantity
M25310-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bromoacetamido-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1807534-79-7

Molecular Weight: 342.18

Formula: C11H20BrNO6

Chemical Name: 3-(2-{2-[2-(2-bromoacetamido)ethoxy]ethoxy}ethoxy)propanoic acid

Smiles: OC(=O)CCOCCOCCOCCNC(=O)CBr

InChiKey: NZRUJYJTSFKZEG-UHFFFAOYSA-N

InChi: InChI=1S/C11H20BrNO6/c12-9-10(14)13-2-4-18-6-8-19-7-5-17-3-1-11(15)16/h1-9H2,(H,13,14)(H,15,16)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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