DSPE-PEG-Biotin (MW 2000)


Catalog No. Size PriceQuantity
M25320-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 385437-57-0

Molecular Weight: 1128.48

Formula: C56H105N4NaO13PS

Chemical Name: [2,3-bis(octadecanoyloxy)propoxy]({2-[({2-[2-(5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanamido)ethoxy]ethoxy}carbonyl)amino]ethoxy})phosphinic acid sodium

Smiles: [Na].CCCCCCCCCCCCCCCCCC(=O)OC(COP(O)(=O)OCCNC(=O)OCCOCCNC(=O)CCCCC1SCC2NC(=O)NC12)COC(=O)CCCCCCCCCCCCCCCCC |^1:0|

InChiKey: ZLACUSWIJZHDBQ-UHFFFAOYSA-N

InChi: InChI=1S/C56H105N4O13PS.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-37-52(62)70-45-48(73-53(63)38-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-72-74(66,67)71-42-40-58-56(65)69-44-43-68-41-39-57-51(61)36-34-33-35-50-54-49(47-75-50)59-55(64)60-54;/h48-50,54H,3-47H2,1-2H3,(H,57,61)(H,58,65)(H,66,67)(H2,59,60,64);

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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