Diazo Biotin-PEG3-azide


Catalog No. Size PriceQuantity
M25353-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1339202-33-3

Molecular Weight: 711.83

Formula: C33H45N9O7S

Chemical Name: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-{2-[2-(2-{2-[(4-{2-[5-(2-azidoethyl)-2-hydroxyphenyl]diazen-1-yl}phenyl)formamido]ethoxy}ethoxy)ethoxy]ethyl}pentanamide

Smiles: [N-]=[N+]=NCCC1=CC(N=NC2C=CC(=CC=2)C(=O)NCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)=C(O)C=C1

InChiKey: VQJUOWXTLWKWGJ-GKVYSXGOSA-N

InChi: InChI=1S/C33H45N9O7S/c34-42-37-12-11-23-5-10-28(43)26(21-23)41-40-25-8-6-24(7-9-25)32(45)36-14-16-48-18-20-49-19-17-47-15-13-35-30(44)4-2-1-3-29-31-27(22-50-29)38-33(46)39-31/h5-10,21,27,29,31,43H,1-4,11-20,22H2,(H,35,44)(H,36,45)(H2,38,39,46)/b41-40+/t27-,29-,31-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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