Description
Boc-NH-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1447797-72-9
Molecular Weight: 371.45
Formula: C14H29NO8S
Chemical Name: tert-butyl N-[2-(2-{2-[2-(methanesulfonyloxy)ethoxy]ethoxy}ethoxy)ethyl]carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOS(C)(=O)=O
InChiKey: ALCCXXPVRZCVPC-UHFFFAOYSA-N
InChi: InChI=1S/C14H29NO8S/c1-14(2,3)23-13(16)15-5-6-19-7-8-20-9-10-21-11-12-22-24(4,17)18/h5-12H2,1-4H3,(H,15,16)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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