Boc-NH-PEG2-C2-NHS ester


Catalog No. Size PriceQuantity
M25416-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2183440-73-3

Molecular Weight: 374.39

Formula: C16H26N2O8

Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]propanoate

Smiles: CC(C)(C)OC(=O)NCCOCCOCCC(=O)ON1C(=O)CCC1=O

InChiKey: FNZXIPYAXFROBS-UHFFFAOYSA-N

InChi: InChI=1S/C16H26N2O8/c1-16(2,3)25-15(22)17-7-9-24-11-10-23-8-6-14(21)26-18-12(19)4-5-13(18)20/h4-11H2,1-3H3,(H,17,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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