Cbz-NH-PEG5-CH2COOH


Catalog No. Size PriceQuantity
M25473-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1449390-66-2

Molecular Weight: 429.46

Formula: C20H31NO9

Chemical Name: 17-{[(benzyloxy)carbonyl]amino}-3,6,9,12,15-pentaoxaheptadecanoic acid

Smiles: OC(=O)COCCOCCOCCOCCOCCNC(=O)OCC1C=CC=CC=1

InChiKey: JEVLWNSJFGPKCP-UHFFFAOYSA-N

InChi: InChI=1S/C20H31NO9/c22-19(23)17-29-15-14-28-13-12-27-11-10-26-9-8-25-7-6-21-20(24)30-16-18-4-2-1-3-5-18/h1-5H,6-17H2,(H,21,24)(H,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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