Description
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Product information
CAS Number: 2149584-03-0
Molecular Weight: 620.74
Formula: C37H40N4O5
Chemical Name: (9H-fluoren-9-yl)methyl N-[(5S)-5-[(2S)-2-amino-3-phenylpropanamido]-5-{[4-(hydroxymethyl)phenyl]carbamoyl}pentyl]carbamate
Smiles: N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21)C(=O)NC1C=CC(CO)=CC=1
InChiKey: RCPHMUPZDFKBDS-HEVIKAOCSA-N
InChi: InChI=1S/C37H40N4O5/c38-33(22-25-10-2-1-3-11-25)35(43)41-34(36(44)40-27-19-17-26(23-42)18-20-27)16-8-9-21-39-37(45)46-24-32-30-14-6-4-12-28(30)29-13-5-7-15-31(29)32/h1-7,10-15,17-20,32-34,42H,8-9,16,21-24,38H2,(H,39,45)(H,40,44)(H,41,43)/t33-,34-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (161.10 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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