Fmoc-Phe-Lys(Boc)-PAB-PNP


Catalog No. Size PriceQuantity
M25486-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 1646299-50-4

Molecular Weight: 885.96

Formula: C49H51N5O11

Chemical Name: {4-[(2S)-6-{[(tert-butoxy)carbonyl]amino}-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-phenylpropanamido]hexanamido]phenyl}methyl 4-nitrophenyl carbonate

Smiles: CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21)C(=O)NC1C=CC(COC(=O)OC2C=CC(=CC=2)[N+]([O-])=O)=CC=1

InChiKey: AHKVECQGASADRU-MJPWBCPGSA-N

InChi: InChI=1S/C49H51N5O11/c1-49(2,3)65-46(57)50-28-12-11-19-42(44(55)51-34-22-20-33(21-23-34)30-63-48(59)64-36-26-24-35(25-27-36)54(60)61)52-45(56)43(29-32-13-5-4-6-14-32)53-47(58)62-31-41-39-17-9-7-15-37(39)38-16-8-10-18-40(38)41/h4-10,13-18,20-27,41-43H,11-12,19,28-31H2,1-3H3,(H,50,57)(H,51,55)(H,52,56)(H,53,58)/t42-,43-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 6 mg/mL (6.77 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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