Quinaldopeptin


Catalog No. Size PriceQuantity
M25535-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Quinaldopeptin, a quinomycin antibiotic isolated from the culture of Streptoverticillium album strain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells.

Product information

CAS Number: 130743-07-6

Molecular Weight: 1243.37

Formula: C62H78N14O14

Chemical Name: 3-hydroxy-N-[27-(3-hydroxyquinoline-2-amido)-4,15,28,39-tetramethyl-2,6,13,16,19,26,30,37,40,43-decaoxo-1,5,12,15,18,25,29,36,39,42-decaazapentacyclo[42.4.0.0⁷,¹².0²⁰,²⁵.0³¹,³⁶]octatetracontan-3-yl]quinoline-2-carboxamide

Smiles: CN1CC(=O)N2CCCCC2C(=O)NC(C)C(NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCCC2C(=O)NCC(=O)N(C)CC(=O)N2CCCCC2C(=O)NC(C)C(NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCCC2C(=O)NCC1=O

InChiKey: KIPSHYPQCJYONU-UHFFFAOYSA-N

InChi: InChI=1S/C62H78N14O14/c1-35-51(69-59(87)53-45(77)29-37-17-5-7-19-39(37)67-53)61(89)75-27-15-11-21-41(75)55(83)63-31-47(79)72(4)34-50(82)74-26-14-10-24-44(74)58(86)66-36(2)52(70-60(88)54-46(78)30-38-18-6-8-20-40(38)68-54)62(90)76-28-16-12-22-42(76)56(84)64-32-48(80)71(3)33-49(81)73-25-13-9-23-43(73)57(85)65-35/h5-8,17-20,29-30,35-36,41-44,51-52,77-78H,9-16,21-28,31-34H2,1-4H3,(H,63,83)(H,64,84)(H,65,85)(H,66,86)(H,69,87)(H,70,88)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Quinaldopeptin is quite active against B16-F10 cells with IC50 values approximately 3-fold superior to that of chromomycin A3.

In Vivo:

Quinaldopeptin shows slight prolongation of life-span in P388-bearing mice at 0.03~0.01 mg/kg, but the antitumor activities is quite limited.

Products are for research use only. Not for human use.

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