Description
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
Product information
CAS Number: 306305-07-7
Molecular Weight: 275.26
Formula: C12H13N5O3
Chemical Name: (2R)-5-(6-amino-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)oxolan-3-ol
Smiles: C#C[C@]1(CO)OC(CC1O)N1C=NC2=C(N)N=CN=C12
InChiKey: HMIGVKANVVLEOA-WZQIAMPNSA-N
InChi: InChI=1S/C12H13N5O3/c1-2-12(4-18)7(19)3-8(20-12)17-6-16-9-10(13)14-5-15-11(9)17/h1,5-8,18-19H,3-4H2,(H2,13,14,15)/t7?,8?,12-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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