Endoxifen E-isomer hydrochloride


Catalog No. Size PriceQuantity
M25724-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer drug substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects.

Product information

CAS Number: 1197194-61-8

Molecular Weight: 409.95

Formula: C25H28ClNO2

Chemical Name: 4-[(1E)-1-{4-[2-(methylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol hydrochloride

Smiles: Cl.CC/C(=C(/C1C=CC(O)=CC=1)\C1C=CC(=CC=1)OCCNC)/C1C=CC=CC=1

InChiKey: RPFIMPDXTABYCN-QREUMGABSA-N

InChi: InChI=1S/C25H27NO2.ClH/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(27)14-10-20)21-11-15-23(16-12-21)28-18-17-26-2;/h4-16,26-27H,3,17-18H2,1-2H3;1H/b25-24+;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 30 mg/mL (73.18 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Endoxifen E-isomer (1-1000 nM; 12 h) inhibits PGR gene expression in E2-induced MCF-7 cells.

Products are for research use only. Not for human use.

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