Description
BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
Product information
CAS Number: 654059-21-9
Molecular Weight: 266.34
Formula: C14H22N2O3
Chemical Name: 3-methyl-2-[(3S)-3-methylpiperidine-1-carbonyl]-4-(propan-2-yl)-2,5-dihydro-1,2-oxazol-5-one
Smiles: CC1=C(C(C)C)C(=O)ON1C(=O)N1CCC[C@H](C)C1
InChiKey: XWESKOHENXWEAX-JTQLQIEISA-N
InChi: InChI=1S/C14H22N2O3/c1-9(2)12-11(4)16(19-13(12)17)14(18)15-7-5-6-10(3)8-15/h9-10H,5-8H2,1-4H3/t10-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (938.65 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
BAY 59-9435 significantly diminishes the isoproterenol-increased media IL-6. BAY 59-9435 blocks isoproterenol-induced SphK1 expression.
Products are for research use only. Not for human use.
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