Purpurin 18 methyl ester


Catalog No. Size PriceQuantity
M25974-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death.

Product information

CAS Number: 51744-55-9

Molecular Weight: 578.66

Formula: C34H34N4O5

Chemical Name: methyl 3-[(22S)-17-ethenyl-12-ethyl-3-hydroxy-13,18,22,27-tetramethyl-5-oxo-4-oxa-8,24,25,26-tetraazahexacyclo[19.2.1.1⁶,⁹.1¹¹,¹⁴.1¹⁶,¹⁹.0²,⁷]heptacosa-1(23),2,6(27),7,9,11(26),12,14,16,18,20-undecaen-23-yl]propanoate

Smiles: COC(=O)CCC1[C@H](C)C2=CC3NC(C=C4N=C(C=C5N=C6C(C(=O)OC(O)=C6C=1N2)=C5C)C(CC)=C4C)=C(C=C)C=3C

InChiKey: DSBPKOBGFPQJGR-NXMWDSTHSA-N

InChi: InChI=1S/C34H34N4O5/c1-8-19-15(3)22-12-24-17(5)21(10-11-28(39)42-7)31(37-24)30-32-29(33(40)43-34(30)41)18(6)25(38-32)14-27-20(9-2)16(4)23(36-27)13-26(19)35-22/h8,12-14,17,35,37,41H,1,9-11H2,2-7H3/b23-13-,24-12-,25-14-/t17-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Purpurin 18 methyl ester (1-5 μg/mL; 24 h) has no cytotoxicity in dark in HepG-2 cells. Purpurin 18 methyl ester (1-5 μg/mL; 24 h) decreases the viability of HepG-2 cells in a concentration-dependent manner with irradiation for 10 min. Purpurin 18 methyl ester (0-24 h) is released from GO- Purpurin 18 methyl ester (Pu18) composite, with rates of 47%, 22% and 30% in weak acidic condition (pH 5.6), neutral environment (pH 7.4) and weak alkali condition (pH 8.9) for 24 h, respectively.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed