Glufosinate


Catalog No. Size PriceQuantity
M26030-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate exerts neurotoxic activity.

Product information

CAS Number: 51276-47-2

Molecular Weight: 181.13

Formula: C5H12NO4P

Chemical Name: 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid

Smiles: CP(O)(=O)CCC(N)C(O)=O

InChiKey: IAJOBQBIJHVGMQ-UHFFFAOYSA-N

InChi: InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Glufosinate (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs). Glufosinate (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM. Glufosinate impairs ependymal cell capability to synthetize cilia.

In Vivo:

Glufosinate (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats. The Elimination of Glufosinate (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats.

Products are for research use only. Not for human use.

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