AD 0261


Catalog No. Size PriceQuantity
M26096-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.

Product information

CAS Number: 145600-69-7

Molecular Weight: 451.55

Formula: C27H31F2N3O

Chemical Name: 2-[(3-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}propyl)amino]-4-methylphenol

Smiles: CC1=CC(NCCCN2CCN(CC2)C(C2C=CC(F)=CC=2)C2C=CC(F)=CC=2)=C(O)C=C1

InChiKey: NVYQVXULNKIDMV-UHFFFAOYSA-N

InChi: InChI=1S/C27H31F2N3O/c1-20-3-12-26(33)25(19-20)30-13-2-14-31-15-17-32(18-16-31)27(21-4-8-23(28)9-5-21)22-6-10-24(29)11-7-22/h3-12,19,27,30,33H,2,13-18H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

AD 0261 displays strong inhibitory action on the generation of lipid peroxides (IC50=0.022 μM) and superoxide anions (IC50= 0.9-4.0 μM). AD 0261 inhibits cytokine release and/or production from PHA-P-stimulated lymphocytes in a dose-dependent manner. AD 0261 inhibits all parameters which are indicative of lymphocyte activation with 50% inhibition being achieved in a range of 1-10 μM. AD 0261 suppresses ornithine decarboxylase activity, the IC50 value being around 1.0 μM.

Products are for research use only. Not for human use.

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