Nampt-IN-3 - CAS# 2121591-52-2


Catalog No. Size PriceQuantity
M26101-C Contact sales@xcessbio.com for quotation $100

Description

Nampt-IN-3 (Compound 35) simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC with IC50s of 31 nM and 55 nM, respectively. Nampt-IN-3 effectively induces cell apoptosis and autophagy and ultimately leads to cell death.

Product information

CAS Number: 2121591-52-2

Molecular Weight: 503.55

Formula: C29H25N7O2

Chemical Name: 4-[1-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)-1H-1,2,3-triazol-4-yl]-N-[(pyridin-3-yl)methyl]benzamide

Smiles: NC1=CC=CC=C1NC(=O)C1C=CC(CN2C=C(N=N2)C2C=CC(=CC=2)C(=O)NCC2C=NC=CC=2)=CC=1

InChiKey: LSGNVZAEAAZOEH-UHFFFAOYSA-N

InChi: InChI=1S/C29H25N7O2/c30-25-5-1-2-6-26(25)33-29(38)24-9-7-20(8-10-24)18-36-19-27(34-35-36)22-11-13-23(14-12-22)28(37)32-17-21-4-3-15-31-16-21/h1-16,19H,17-18,30H2,(H,32,37)(H,33,38)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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