CB-7921220


Catalog No. Size PriceQuantity
M26205-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CB-7921220 is an adenylate cyclase inhibitor.

Product information

CAS Number: 115453-99-1

Molecular Weight: 240.26

Formula: C14H12N2O2

Chemical Name: 6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid

Smiles: NC1C=CC(/C=C/C2=CC=CC(=N2)C(O)=O)=CC=1

InChiKey: QASPDWZDKLUOPO-RMKNXTFCSA-N

InChi: InChI=1S/C14H12N2O2/c15-11-7-4-10(5-8-11)6-9-12-2-1-3-13(16-12)14(17)18/h1-9H,15H2,(H,17,18)/b9-6+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (208.11 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6.

Products are for research use only. Not for human use.

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