Description
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity.
Product information
CAS Number: 26929-65-7
Molecular Weight: 269.21
Formula: C9H11N5O5
Chemical Name: 1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Smiles: [N-]=[N+]=N[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N1C=CC(=O)NC1=O
InChiKey: MRUKYOQQKHNMFI-XVFCMESISA-N
InChi: InChI=1S/C9H11N5O5/c10-13-12-6-7(17)4(3-15)19-8(6)14-2-1-5(16)11-9(14)18/h1-2,4,6-8,15,17H,3H2,(H,11,16,18)/t4-,6-,7-,8-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
2'-Azido-2'-deoxyuridine (N3dUrd) has IC50s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell.
Products are for research use only. Not for human use.
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