Description
Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities.
Product information
CAS Number: 28178-92-9
Molecular Weight: 354.40
Formula: C21H22O5
Chemical Name: 4-[(1E)-1-(2H-1,3-benzodioxol-5-yl)prop-1-en-2-yl]-4,5-dimethoxy-2-(prop-2-en-1-yl)cyclohexa-2,5-dien-1-one
Smiles: C/C(=C\C1=CC2OCOC=2C=C1)/C1(C=C(CC=C)C(=O)C=C1OC)OC
InChiKey: AOZTYYBGNNXAOI-NTEUORMPSA-N
InChi: InChI=1S/C21H22O5/c1-5-6-16-12-21(24-4,20(23-3)11-17(16)22)14(2)9-15-7-8-18-19(10-15)26-13-25-18/h5,7-12H,1,6,13H2,2-4H3/b14-9+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Futoquinol potently inhibits NO production with an IC50 value of 16.8 μM in LPS-activated BV-2 cells, a microglia cell line.
Products are for research use only. Not for human use.
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