Aldehyde-benzyl-PEG5-alkyne


Catalog No. Size PriceQuantity
M26754-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1378928-83-6

Molecular Weight: 350.41

Formula: C19H26O6

Chemical Name: 4-(3,6,9,12-tetraoxahexadec-15-yn-1-yloxy)benzaldehyde

Smiles: C#CCCOCCOCCOCCOCCOC1C=CC(C=O)=CC=1

InChiKey: AALNWPTUBYAKQV-UHFFFAOYSA-N

InChi: InChI=1S/C19H26O6/c1-2-3-8-21-9-10-22-11-12-23-13-14-24-15-16-25-19-6-4-18(17-20)5-7-19/h1,4-7,17H,3,8-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Products are for research use only. Not for human use.

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