DNP-PEG4-acid


Catalog No. Size PriceQuantity
M26784-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DNP-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 858126-76-8

Molecular Weight: 431.39

Formula: C17H25N3O10

Chemical Name: 1-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: [O-][N+](=O)C1=CC(=CC=C1NCCOCCOCCOCCOCCC(O)=O)[N+]([O-])=O

InChiKey: PTIFQVOBASTCFB-UHFFFAOYSA-N

InChi: InChI=1S/C17H25N3O10/c21-17(22)3-5-27-7-9-29-11-12-30-10-8-28-6-4-18-15-2-1-14(19(23)24)13-16(15)20(25)26/h1-2,13,18H,3-12H2,(H,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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