Description
Benzyl-PEG5-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 230620-74-3
Molecular Weight: 412.52
Formula: C22H36O7
Chemical Name: 2-[(1-phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl)oxy]oxane
Smiles: C(OCCOCCOCCOCCOCCOC1CCCCO1)C1C=CC=CC=1
InChiKey: WQRPIBUKQARHFH-UHFFFAOYSA-N
InChi: InChI=1S/C22H36O7/c1-2-6-21(7-3-1)20-27-17-16-25-13-12-23-10-11-24-14-15-26-18-19-29-22-8-4-5-9-28-22/h1-3,6-7,22H,4-5,8-20H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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