Description
Propargyl-PEG2-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 145916-41-2
Molecular Weight: 254.30
Formula: C12H14O4S
Chemical Name: 2-(prop-2-yn-1-yloxy)ethyl 4-methylbenzene-1-sulfonate
Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCCOCC#C
InChiKey: KTEIFCKZGZZTHP-UHFFFAOYSA-N
InChi: InChI=1S/C12H14O4S/c1-3-8-15-9-10-16-17(13,14)12-6-4-11(2)5-7-12/h1,4-7H,8-10H2,2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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