Azido-PEG3-amide-C3-triethoxysilane


Catalog No. Size PriceQuantity
M26828-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2243566-43-8

Molecular Weight: 450.60

Formula: C18H38N4O7Si

Chemical Name: 3-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}-N-[3-(triethoxysilyl)propyl]propanamide

Smiles: CCO[Si](CCCNC(=O)CCOCCOCCOCCN=[N+]=[N-])(OCC)OCC

InChiKey: BCFMWIGPFZSBNT-UHFFFAOYSA-N

InChi: InChI=1S/C18H38N4O7Si/c1-4-27-30(28-5-2,29-6-3)17-7-9-20-18(23)8-11-24-13-15-26-16-14-25-12-10-21-22-19/h4-17H2,1-3H3,(H,20,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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