DNP-PEG4-DBCO


Catalog No. Size PriceQuantity
M26846-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2149585-17-9

Molecular Weight: 689.71

Formula: C35H39N5O10

Chemical Name: N-(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)-1-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadecan-15-amide

Smiles: [O-][N+](=O)C1=CC(=CC=C1NCCOCCOCCOCCOCCC(=O)NCCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12)[N+]([O-])=O

InChiKey: QEBKLLLFFHAWSF-UHFFFAOYSA-N

InChi: InChI=1S/C35H39N5O10/c41-34(37-15-13-35(42)38-26-29-7-2-1-5-27(29)9-10-28-6-3-4-8-32(28)38)14-17-47-19-21-49-23-24-50-22-20-48-18-16-36-31-12-11-30(39(43)44)25-33(31)40(45)46/h1-8,11-12,25,36H,13-24,26H2,(H,37,41)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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