Cbz-NH-PEG5-C2-acid


Catalog No. Size PriceQuantity
M26889-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1347750-74-6

Molecular Weight: 443.49

Formula: C21H33NO9

Chemical Name: 1-{[(benzyloxy)carbonyl]amino}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCOCCNC(=O)OCC1C=CC=CC=1

InChiKey: XDNKBFYOBNNSEF-UHFFFAOYSA-N

InChi: InChI=1S/C21H33NO9/c23-20(24)6-8-26-10-12-28-14-16-30-17-15-29-13-11-27-9-7-22-21(25)31-18-19-4-2-1-3-5-19/h1-5H,6-18H2,(H,22,25)(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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