1, 1, 1-Trifluoroethyl-PEG4-Tos


Catalog No. Size PriceQuantity
M26910-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1872433-61-8

Molecular Weight: 430.44

Formula: C17H25F3O7S

Chemical Name: 14,14,14-trifluoro-3,6,9,12-tetraoxatetradecan-1-yl 4-methylbenzene-1-sulfonate

Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOCC(F)(F)F

InChiKey: UYAXEKCLHRTXQU-UHFFFAOYSA-N

InChi: InChI=1S/C17H25F3O7S/c1-15-2-4-16(5-3-15)28(21,22)27-13-12-25-9-8-23-6-7-24-10-11-26-14-17(18,19)20/h2-5H,6-14H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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