Propargyl-PEG4-S-PEG4-propargyl


Catalog No. Size PriceQuantity
M26914-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055041-17-1

Molecular Weight: 462.60

Formula: C22H38O8S

Chemical Name: 4,7,10,13,19,22,25,28-octaoxa-16-thiahentriaconta-1,30-diyne

Smiles: C#CCOCCOCCOCCOCCSCCOCCOCCOCCOCC#C

InChiKey: FWWYVRGWJPDTIG-UHFFFAOYSA-N

InChi: InChI=1S/C22H38O8S/c1-3-5-23-7-9-25-11-13-27-15-17-29-19-21-31-22-20-30-18-16-28-14-12-26-10-8-24-6-4-2/h1-2H,5-22H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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