Propargyl-PEG10-acid


Catalog No. Size PriceQuantity
M26919-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Propargyl-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055022-18-7

Molecular Weight: 524.60

Formula: C24H44O12

Chemical Name: 4,7,10,13,16,19,22,25,28,31-decaoxatetratriacont-33-ynoic acid

Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

InChiKey: ALHRCZLKCUZEQF-UHFFFAOYSA-N

InChi: InChI=1S/C24H44O12/c1-2-4-27-6-8-29-10-12-31-14-16-33-18-20-35-22-23-36-21-19-34-17-15-32-13-11-30-9-7-28-5-3-24(25)26/h1H,3-23H2,(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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