Boc-C16-NHS ester


Catalog No. Size PriceQuantity
M26928-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 843666-34-2

Molecular Weight: 467.64

Formula: C26H45NO6

Chemical Name: 1-tert-butyl 2,5-dioxopyrrolidin-1-yl octadecanedioate

Smiles: CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O

InChiKey: JTOVMMPSILRQQJ-UHFFFAOYSA-N

InChi: InChI=1S/C26H45NO6/c1-26(2,3)32-24(30)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-25(31)33-27-22(28)20-21-23(27)29/h4-21H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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