Description
S-acetyl-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1818294-25-5
Molecular Weight: 494.62
Formula: C21H34O9S2
Chemical Name: 1-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15-pentaoxa-18-thiaicosan-19-one
Smiles: CC(=O)SCCOCCOCCOCCOCCOCCOS(=O)(=O)C1C=CC(C)=CC=1
InChiKey: REKKYTBDWPWJBY-UHFFFAOYSA-N
InChi: InChI=1S/C21H34O9S2/c1-19-3-5-21(6-4-19)32(23,24)30-16-15-28-12-11-26-8-7-25-9-10-27-13-14-29-17-18-31-20(2)22/h3-6H,7-18H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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